Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428178 | 0.87 | MAPT (0.55) | HTR1AHTR2AHRH1ALDH1A1MAOB | |
| SCHEMBL9387918 | 0.85 | HTR1A (0.51) | HTR1AHTR2AHRH1ALDH1A1MAOB | |
| SCHEMBL9428383 | 0.84 | MAPT (0.59) | HTR1AHRH1MAOBLMNA | |
| SCHEMBL9429316 | 0.83 | ALDH1A1 (0.46) | HTR1AHTR2AALDH1A1THRBMAOB | |
| SCHEMBL9429134 | 0.83 | HRH1 (0.43) | HRH1ALDH1A1 | |
| SCHEMBL9429336 | 0.82 | HRH3 (0.55) | HTR1AHTR2A | |
| SCHEMBL9388964 | 0.82 | HTR1A (0.50) | HTR1AHTR2AHRH1ALDH1A1MAOB | |
| SCHEMBL9428210 | 0.82 | ADRA1B (0.47) | HTR1AHRH1ALDH1A1THRBLMNA | |
| SCHEMBL9428955 | 0.82 | ALDH1A1 (0.45) | HTR1AHTR2AHRH1ALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL9429865 | 0.81 | HRH3 (0.54) | HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |