SCHEMBL942974

SCHEMBL942974

O=C(Oc1ccccc1SSc1ccccc1OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 7/20 0.61
▸ MAPT P10636 4/20 0.61
▸ SMN1; SMN2 Q16637 2/20 0.61
▸ SLC6A3 Q01959 1/20 0.54
▸ ESR1 P03372 2/20 0.53
▸ ESR2 Q92731 2/20 0.53
▸ HSD17B10 Q99714 2/20 0.53
▸ MEN1 O00255 2/20 0.53
▸ GAA P10253 2/20 0.53
▸ JAK2 O60674 1/20 0.53
▸ USP2 O75604 1/20 0.53
▸ ALOX15 P16050 1/20 0.53
▸ NPSR1 Q6W5P4 1/20 0.53
▸ LMNA P02545 2/20 0.49
▸ METAP2 P50579 1/20 0.49
▸ METAP1 P53582 1/20 0.49
▸ HDAC6 Q9UBN7 1/20 0.49
▸ TOP1 P11387 1/20 0.49
▸ F2 P00734 1/20 0.48
▸ POLB P06746 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9687652 0.85 KMT2A (0.58) KMT2AMAPTSMN1; SMN2SLC6A3ESR1
SCHEMBL27801075 0.84 KMT2A (0.56) KMT2AMAPTSMN1; SMN2SLC6A3ESR1
SCHEMBL725404 0.83 KMT2A (0.76) KMT2AMAPTSMN1; SMN2SLC6A3ESR1
Bromide SCHEMBL29588519 0.81 KMT2A (0.73) KMT2AMAPTSMN1; SMN2SLC6A3ESR1
Hydrochloric Acid SCHEMBL16050041 0.81 KMT2A (0.73) KMT2AMAPTSMN1; SMN2SLC6A3ESR1
SCHEMBL6967920 0.80 KMT2A (0.66) KMT2AMAPTSMN1; SMN2SLC6A3ESR1
SCHEMBL31517375 0.78 KMT2A (0.68) KMT2AMAPTSMN1; SMN2SLC6A3ESR1
Acetic Acid SCHEMBL29588064 0.78 KMT2A (0.68) KMT2AMAPTSMN1; SMN2SLC6A3ESR1
SCHEMBL3826754 0.76 KMT2A (0.66) KMT2AMAPTSMN1; SMN2SLC6A3ESR1
SCHEMBL6972608 0.76 KMT2A (0.66) KMT2AMAPTSMN1; SMN2SLC6A3ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987516-B2 Process for producing arylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2015-03-24 — — US disclosed
EP-2468722-B1 Process for producing arylsulfur halotetrafluorides UBE INDUSTRIES (JP) 2014-10-01 — — EP disclosed
EP-2468721-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2014-02-26 — — EP disclosed
EP-2468720-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-11-27 — — EP disclosed
EP-2468719-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-10-16 — — EP disclosed
EP-2137144-B1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES UBE INDUSTRIES (JP) 2013-07-31 — — EP disclosed
US-8399720-B2 Methods for producing fluorinated phenylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2013-03-19 — — US disclosed
EP-2468722-A1 Process for producing arylsulfur halotetrafluorides UBE Industries, Ltd. (JP) 2012-06-27 — — EP disclosed
EP-2468721-A1 Process for producing arylsulfur pentafluorides UBE Industries, Ltd. (JP) 2012-06-27 — — EP disclosed
EP-2468720-A1 Process for producing arylsulfur pentafluorides UBE Industries, Ltd. (JP) 2012-06-27 — — EP disclosed
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-05-27 — — US disclosed
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-03-25 — — US disclosed
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-02-04 — — US disclosed
WO-2010014665-A1 METHODS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2010-02-04 — — WO disclosed
EP-2137144-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T Research, Inc. (US) 2009-12-30 — — EP disclosed
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2009-11-19 — — US disclosed
US-7592491-B2 Process for producing arylsulfur pentafluorides IM&T RESEARCH, INC. (US) 2009-09-22 — — US disclosed
WO-2008118787-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM & T RESEARCH, INC. (US) 2008-10-02 — — WO disclosed
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2008-09-25 — — US disclosed
US-5194539-A Of ethylenically unsaturated monomers where the aqueous dispersion is free from odor causing xanthogen disulfide RHONE-POULENC CHIMIE (FR) 1993-03-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA KMT2A 3642/4885MAPT 3764/4885SMN1; SMN2 2262/4885
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides BRPF1, SFXN3, SLFN12 KMT2A 3382/4885MAPT 3665/4885SMN1; SMN2 768/4885
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA KMT2A 3642/4885MAPT 3764/4885SMN1; SMN2 2262/4885
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES PFAS, MPST, ARSA KMT2A 3642/4885MAPT 3764/4885SMN1; SMN2 2262/4885
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA KMT2A 3642/4885MAPT 3764/4885SMN1; SMN2 2262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback