Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430322 | 0.84 | HTT (0.41) | HTTATML3MBTL1MAPTPKM | |
| SCHEMBL3150589 | 0.75 | ATM (0.45) | HTTATML3MBTL1PKMKDM4E | |
| SCHEMBL8048116 | 0.75 | TSHR (0.43) | HTTMAPTPKMKDM4EALDH1A1 | |
| SCHEMBL7708841 | 0.75 | TSHR (0.43) | HTTMAPTPKMKDM4EALDH1A1 | |
| SCHEMBL8037300 | 0.75 | TSHR (0.43) | HTTMAPTPKMKDM4EALDH1A1 | |
| SCHEMBL8328348 | 0.73 | ATM (0.45) | HTTATML3MBTL1PKMKDM4E | |
| SCHEMBL8055172 | 0.69 | HSD17B1 (0.44) | MAPTMAPK1MEN1KMT2A | |
| SCHEMBL8047432 | 0.69 | HSD17B1 (0.44) | MAPTMAPK1MEN1KMT2A | |
| SCHEMBL8055202 | 0.68 | MEN1 (0.42) | HTTMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL8037341 | 0.68 | ALDH1A1 (0.43) | HTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374727-A | Using rhodium-diphosphine complex as hydrogenation catalyst | HOFFMANN-LA ROCHE INC. (US) | 1994-12-20 | — | — | US | disclosed |