Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431302 | 0.91 | L3MBTL1 (0.49) | PTPN1KMT2AMEN1ATMNPC1 | |
| Hydrochloric Acid SCHEMBL9213805 | 0.90 | L3MBTL1 (0.48) | PTPN1KMT2AMEN1ATMNPC1 | |
| SCHEMBL9431764 | 0.87 | L3MBTL1 (0.43) | PTPN1KMT2AMEN1ATMNPC1 | |
| Hydrochloric Acid SCHEMBL9216724 | 0.86 | L3MBTL1 (0.42) | PTPN1KMT2AMEN1ATMNPC1 | |
| Hydrochloric Acid SCHEMBL9220707 | 0.84 | L3MBTL1 (0.43) | PTPN1KMT2AMEN1NPC1ANO1 | |
| Hydrochloric Acid SCHEMBL9215520 | 0.83 | L3MBTL1 (0.52) | PTPN1ATMNPC1 | |
| SCHEMBL9217698 | 0.83 | L3MBTL1 (0.40) | PTPN1MAOBKMT2AMEN1ATM | |
| SCHEMBL9430879 | 0.83 | L3MBTL1 (0.42) | PTPN1KMT2AMEN1ATMNPC1 | |
| SCHEMBL9430543 | 0.83 | ALDH1A1 (0.53) | PTPN1MAOBKMT2ASLC26A4NPC1 | |
| SCHEMBL9218346 | 0.82 | NPC1 (0.53) | PTPN1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026738-A1 | N'-HETEROCYCLYL-N-BENZOFURANYL UREA DERIVATIVES AND THEIR ANALOGS AS ACAT INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |