Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.43 |
| ▸ | ALAD | P13716 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | THPO | P40225 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467541 | 0.71 | EGFR (0.45) | ALDH1A1SMN1; SMN2HIF1ALMNAMAPT | |
| SCHEMBL6177213 | 0.69 | BCL2L1 (0.47) | ALDH1A1SMN1; SMN2HIF1ALMNAMAPT | |
| SCHEMBL7372088 | 0.68 | DAO (0.59) | DAOALADMAPTGSK3B | |
| SCHEMBL766052 | 0.67 | EGFR (0.61) | ALDH1A1SMN1; SMN2HIF1ALMNAMAPT | |
| SCHEMBL7470725 | 0.66 | EGFR (0.51) | ALDH1A1SMN1; SMN2HIF1ALMNAMAPT | |
| SCHEMBL788121 | 0.65 | — | — | |
| SCHEMBL29264781 | 0.65 | — | — | |
| SCHEMBL30204903 | 0.63 | EGFR (0.49) | ALDH1A1SMN1; SMN2HIF1ALMNAMAPT | |
| SCHEMBL28053872 | 0.63 | DAO (0.44) | DAOALADALDH1A1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL11202647 | 0.63 | ALAD (0.58) | DAOALADTSHRALOX15GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310752-A | Distamycin A analogs; antitumor agents, viricides | FARMITALIA CARLO ERBA SPA (IT) | 1994-05-10 | — | — | US | disclosed |
| EP-0246868-B1 | SITE SPECIFIC ALKYLATING AGENTS | FARMITALIA CARLO ERBA S.r.l. (IT) | 1992-09-16 | — | — | EP | disclosed |
| US-5049579-A | Antitumor, viricides | FARMITALIA CARLO ERBA, S.R.L. (IT) | 1991-09-17 | — | — | US | disclosed |
| US-5017599-A | Antitumor, antiviral distamycin A analog | FARMITALIA CARLO ERBA, SPA (IT) | 1991-05-21 | — | — | US | disclosed |
| EP-0246868-A1 | Site specific alkylating agents | FARMITALIA CARLO ERBA S.r.l. (IT) | 1987-11-25 | — | — | EP | disclosed |