Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9792739 | 0.85 | CYP11B1 (0.41) | HCAR2MEN1KMT2AL3MBTL1PDE10A | |
| SCHEMBL9792735 | 0.83 | RAB9A (0.53) | HCAR2MEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL9431457 | 0.83 | HCAR2 (0.36) | HCAR2MEN1KMT2AL3MBTL1PDE10A | |
| SCHEMBL8542357 | 0.80 | RAB9A (0.58) | MEN1KMT2AL3MBTL1HTTMAPK1 | |
| SCHEMBL9468716 | 0.78 | PDE10A (0.39) | PDE10AEP300CREBBPKAT2AKAT2B | |
| SCHEMBL8548181 | 0.76 | TRPA1 (0.43) | HCAR2MEN1KMT2ATRPA1L3MBTL1 | |
| SCHEMBL9383480 | 0.75 | RAB9A (0.55) | MEN1KMT2AL3MBTL1HTTMAPK1 | |
| SCHEMBL9383256 | 0.71 | TRPA1 (0.39) | MEN1KMT2ATRPA1HTTGPR84 | |
| SCHEMBL1870799 | 0.70 | HCAR2 (0.74) | HCAR2 | |
| SCHEMBL1368257 | 0.69 | GPR84 (0.42) | HCAR2MEN1KMT2ATRPA1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350749-A | Fungicides, insecticides and miticides | DOWELANCO (US) | 1994-09-27 | — | — | US | disclosed |
| US-5350749-A | Fungicides, insecticides and miticides | DOWELANCO (US) | 1994-09-27 | — | — | US | disclosed |
| US-5034393-A | Fungicides for plants | DOWELANCO (US) | 1991-07-23 | — | — | US | disclosed |
| US-5034393-A | Fungicides for plants | DOWELANCO (US) | 1991-07-23 | — | — | US | disclosed |
| EP-0414386-A1 | Condensed pyrimidine derivates | DowElanco (US) | 1991-02-27 | — | — | EP | disclosed |