Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 4/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.36 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383256 | 0.94 | TRPA1 (0.39) | TRPA1HTTLMNAPOLBGPR84 | |
| SCHEMBL8548684 | 0.88 | RAB9A (0.42) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL8544014 | 0.87 | ELOVL1 (0.39) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL8545027 | 0.86 | ELOVL1 (0.36) | TRPA1HTTLMNAPOLBNPC1 | |
| SCHEMBL8548285 | 0.86 | GABRA1 (0.39) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL9385263 | 0.85 | EGFR (0.41) | TRPA1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8542280 | 0.85 | AURKA (0.47) | POLBNPC1RAB9ASMN1; SMN2AURKA | |
| SCHEMBL8541261 | 0.84 | ELOVL1 (0.36) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL8547249 | 0.84 | AURKA (0.45) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8543586 | 0.84 | RAB9A (0.51) | HTTLMNAPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411963-A | Plant fungicides, miticides, insecticides | DOWELANCO (US) | 1995-05-02 | — | — | US | claimed |
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5411963-A | Plant fungicides, miticides, insecticides | DOWELANCO (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0326329-A2 | Quinazoline derivatives | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |