Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.43 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542136 | 0.78 | AURKA (0.48) | HTTMAPK1LMNAAPPEGFR | |
| SCHEMBL1437428 | 0.76 | TP53 (0.43) | HTTMAPK1LMNACNR1CNR2 | |
| SCHEMBL13399861 | 0.75 | AURKA (0.74) | HTTMAPK1LMNAAPPEGFR | |
| SCHEMBL8540683 | 0.74 | HTT (0.65) | HTTMAPK1LMNAAPPEGFR | |
| SCHEMBL8542554 | 0.74 | HTT (0.72) | HTTMAPK1LMNAAPPEGFR | |
| SCHEMBL8484236 | 0.72 | LDHA (0.46) | HTTMAPK1LMNAAPPEGFR | |
| SCHEMBL13230422 | 0.70 | EGFR (0.49) | HTTLMNAAPPEGFRMEN1 | |
| SCHEMBL22872908 | 0.69 | AURKA (0.57) | HTTMAPK1LMNAEGFRMEN1 | |
| SCHEMBL11407033 | 0.69 | PIK3CD (0.56) | HTTMAPK1LMNAAPPEGFR | |
| SCHEMBL5264465 | 0.68 | HTT (0.48) | HTTLMNAEGFRCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3066689-A | — | — | None | — | — | JP | disclosed |
| US-5350749-A | Fungicides, insecticides and miticides | DOWELANCO (US) | 1994-09-27 | — | — | US | disclosed |
| US-5034393-A | Fungicides for plants | DOWELANCO (US) | 1991-07-23 | — | — | US | disclosed |
| JP-H0366689-A | PYRIDOPYRIMIDINE DERIVATIVE | ELI LILLY & CO | 1991-03-22 | — | — | JP | disclosed |