Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | F12 | P00748 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218384 | 0.93 | TP53 (0.54) | TP53MAOBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9217396 | 0.82 | TP53 (0.71) | TP53SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL9212323 | 0.81 | L3MBTL1 (0.51) | TP53MAOBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9430605 | 0.80 | TP53 (0.71) | TP53SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL8201626 | 0.80 | L3MBTL1 (0.60) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9431339 | 0.78 | POLB (0.66) | TP53SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL9430103 | 0.78 | TP53 (0.51) | TP53SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL9430382 | 0.78 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9212898 | 0.77 | MAPT (0.48) | TP53MAOBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9430417 | 0.77 | TP53 (0.46) | TP53MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026738-A1 | N'-HETEROCYCLYL-N-BENZOFURANYL UREA DERIVATIVES AND THEIR ANALOGS AS ACAT INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |