Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SLC26A4 | O43511 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432912 | 0.91 | EDNRA (0.60) | EDNRACASP3SENP8SENP7SENP6 | |
| SCHEMBL9432759 | 0.88 | EDNRA (0.54) | EDNRACASP3SENP8SENP7SENP6 | |
| SCHEMBL9434052 | 0.83 | KDM4E (0.53) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL9433079 | 0.81 | EDNRA (0.51) | EDNRACASP3SENP8SENP7SENP6 | |
| SCHEMBL9433674 | 0.81 | ICAM1 (0.56) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL9433730 | 0.79 | KDM4E (0.43) | PKMMEN1KMT2A | |
| SCHEMBL9433007 | 0.79 | ICAM1 (0.53) | MAOBMAOAMEN1KMT2A | |
| SCHEMBL9433895 | 0.77 | KDM4E (0.47) | PKMMEN1KMT2AATM | |
| SCHEMBL720265 | 0.76 | CASP3 (0.60) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470816 | 0.76 | CASP3 (0.80) | CASP3SENP8SENP7SENP6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |