Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SLC26A4 | O43511 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433069 | 0.91 | EDNRA (0.55) | EDNRACASP3SENP8SENP7SENP6 | |
| SCHEMBL9432759 | 0.90 | EDNRA (0.54) | EDNRACASP3SENP8SENP7SENP6 | |
| SCHEMBL9433280 | 0.82 | ANO1 (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL6240452 | 0.82 | KDM4E (0.53) | EDNRACASP3SENP8SENP7SENP6 | |
| SCHEMBL9432922 | 0.81 | EDNRA (0.55) | EDNRACASP3SENP8SENP7SENP6 | |
| SCHEMBL15201819 | 0.80 | CASP3 (0.59) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL9432934 | 0.78 | RXRA (0.47) | CASP3SENP8SENP7SENP6PKM | |
| SCHEMBL720265 | 0.78 | CASP3 (0.60) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL9434157 | 0.77 | KDM4E (0.44) | EDNRAL3MBTL1KDM4EKMT2A | |
| SCHEMBL3535209 | 0.77 | ANO1 (0.67) | KDM4EANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |