Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 2/20 | 0.53 |
| ▸ | SELE | P16581 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432872 | 0.85 | KDM4E (0.59) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9433674 | 0.84 | ICAM1 (0.56) | ICAM1SELEGAAPOLBRAB9A | |
| SCHEMBL9433730 | 0.82 | KDM4E (0.43) | GAARAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL9433895 | 0.81 | KDM4E (0.47) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9433069 | 0.79 | EDNRA (0.55) | MAOBMAOAMEN1KMT2A | |
| SCHEMBL9433019 | 0.76 | ICAM1 (0.48) | ICAM1SELEGAAPOLBRAB9A | |
| SCHEMBL12660566 | 0.74 | KDM4E (0.69) | RAB9AMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL6239679 | 0.73 | GAA (0.57) | ICAM1SELEGAARAB9AKDM4E | |
| SCHEMBL9432874 | 0.72 | MCL1 (0.61) | RAB9AMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL6240452 | 0.71 | KDM4E (0.53) | ICAM1SELEPOLBRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |