Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.45 |
| ▸ | YAP1 | P46937 | 1/20 | 0.45 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.45 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434157 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1AHRHSD17B10TP53 | |
| SCHEMBL1379206 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1TEAD1YAP1TEAD4 | |
| SCHEMBL9433730 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1IRAK4HSD17B10TP53 | |
| SCHEMBL9433172 | 0.82 | SMN1; SMN2 (0.45) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL9433007 | 0.81 | ICAM1 (0.53) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL9432872 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL9433051 | 0.80 | MAPT (0.53) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL9433674 | 0.79 | ICAM1 (0.56) | KDM4EALDH1A1MAPK10HSD17B10TP53 | |
| SCHEMBL9433257 | 0.77 | LMNA (0.54) | KDM4EALDH1A1TP53MAPTHPGD | |
| SCHEMBL9433069 | 0.77 | EDNRA (0.55) | KMT2AMEN1ATMPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |