Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | SELE | P16581 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432880 | 0.84 | KDM4E (0.47) | GAAPARP10MAOBIRAK4KDM4E | |
| SCHEMBL9433688 | 0.83 | ICAM1 (0.51) | ICAM1SELEPOLBPARP10RAB9A | |
| SCHEMBL9433908 | 0.82 | IRAK4 (0.46) | ICAM1SELEGAAPARP10IRAK4 | |
| SCHEMBL9433742 | 0.81 | RXRA (0.43) | GAAPOLBIRAK4RAB9AKDM4E | |
| SCHEMBL9433079 | 0.78 | EDNRA (0.51) | PARP10MAOBMAOARAB9A | |
| SCHEMBL9433007 | 0.76 | ICAM1 (0.53) | ICAM1SELEAKR1B1GAAPOLB | |
| SCHEMBL9432883 | 0.71 | MCL1 (0.48) | GAAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL9433896 | 0.70 | KDM4E (0.51) | ICAM1SELEGAAPOLBRAB9A | |
| SCHEMBL9432939 | 0.69 | RXRA (0.48) | GAAPOLBRAB9AKDM4EALDH1A1 | |
| SCHEMBL9433491 | 0.69 | KDM4E (0.51) | ICAM1SELEGAAMAOARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |