Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5105230 | 0.84 | GRM2 (0.56) | POLBALDH1A1USP2MAPTHPGD | |
| SCHEMBL28849019 | 0.84 | PDE4A (0.46) | POLBALDH1A1USP2MAPTHPGD | |
| SCHEMBL4105055 | 0.83 | POLB (0.51) | POLBALDH1A1USP2MAPTHPGD | |
| SCHEMBL2152756 | 0.83 | BPTF (0.61) | POLBALDH1A1USP2MAPTHPGD | |
| SCHEMBL7456282 | 0.82 | PDE4A (0.50) | POLBALDH1A1USP2MAPTHPGD | |
| SCHEMBL12974281 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2DPP4TP53 | |
| SCHEMBL9659383 | 0.78 | SMN1; SMN2 (0.51) | ALDH1A1MAPTSMN1; SMN2NPC1TSHR | |
| SCHEMBL31716545 | 0.77 | BRD4 (0.58) | POLBALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL14525336 | 0.77 | MTNR1A (0.70) | POLBALDH1A1USP2MAPTNPC1 | |
| SCHEMBL435086 | 0.77 | POLB (0.57) | POLBALDH1A1USP2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302726-A | N-benzyl-4-alkyl-pyrrolidinone herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-04-12 | — | — | US | disclosed |