Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434400 | 1.00 | GLO1 (0.54) | GLO1CYP1A2CYP3A4HIF1AFBP1 | |
| SCHEMBL9433467 | 0.76 | GLO1 (0.56) | GLO1CYP1A2CYP3A4HIF1AFBP1 | |
| SCHEMBL9433473 | 0.76 | GLO1 (0.56) | GLO1CYP1A2CYP3A4HIF1AFBP1 | |
| SCHEMBL9434339 | 0.76 | GLO1 (0.63) | GLO1CYP1A2CYP3A4HIF1AFBP1 | |
| SCHEMBL9434342 | 0.76 | GLO1 (0.63) | GLO1CYP1A2CYP3A4HIF1AFBP1 | |
| SCHEMBL9434385 | 0.75 | GLO1 (0.61) | GLO1CYP1A2CYP3A4HIF1AFBP1 | |
| SCHEMBL9434390 | 0.75 | GLO1 (0.61) | GLO1CYP1A2CYP3A4HIF1AFBP1 | |
| SCHEMBL9434172 | 0.74 | GLO1 (0.54) | GLO1CYP1A2CYP3A4HIF1AFBP1 | |
| SCHEMBL9434178 | 0.74 | GLO1 (0.54) | GLO1CYP1A2CYP3A4HIF1AFBP1 | |
| Acetic Acid SCHEMBL28007455 | 0.73 | POLB (0.48) | CYP1A2CYP3A4MAPTALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |