Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434798 | 0.89 | KMT2A (0.47) | MAPTNPSR1KDM4ELMNACACNA1B | |
| SCHEMBL9433545 | 0.86 | CACNA1B (0.44) | MAPTKDM4ELMNAHTTCACNA1B | |
| SCHEMBL9433577 | 0.85 | PKM (0.47) | KDM4ECACNA1BCACNA1C | |
| SCHEMBL9434851 | 0.84 | KDM4E (0.44) | KDM4ECACNA1BCACNA1CALDH1A1F2 | |
| SCHEMBL9434792 | 0.84 | CACNA1B (0.43) | MAPTCACNA1BCACNA1CKMOALDH1A1 | |
| SCHEMBL9433824 | 0.84 | CACNA1B (0.43) | MAPTKDM4ELMNACACNA1BCACNA1C | |
| SCHEMBL9434480 | 0.83 | PDE1C (0.52) | MAPTKDM4ELMNAHTTCACNA1B | |
| SCHEMBL9434014 | 0.83 | KDM4E (0.45) | MAPTNPSR1KDM4ELMNAHTT | |
| SCHEMBL9433754 | 0.83 | GAA (0.44) | MAPTNPSR1KDM4ELMNACACNA1B | |
| SCHEMBL9434815 | 0.82 | CACNA1C (0.44) | MAPTNPSR1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |