Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434605 | 0.90 | NR1I2 (0.52) | GAAMKNK1MKNK2CACNA1BKDM4E | |
| SCHEMBL9433784 | 0.87 | CYP11B1 (0.48) | GAACACNA1BKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9433545 | 0.86 | CACNA1B (0.44) | GAAMKNK1MKNK2CACNA1BKDM4E | |
| SCHEMBL9433577 | 0.85 | PKM (0.47) | CACNA1BKDM4EPKM | |
| SCHEMBL9433824 | 0.84 | CACNA1B (0.43) | GAAMKNK1MKNK2CACNA1BKDM4E | |
| SCHEMBL9434851 | 0.84 | KDM4E (0.44) | MKNK1MKNK2CACNA1BKDM4EALDH1A1 | |
| SCHEMBL9434792 | 0.84 | CACNA1B (0.43) | GAAMKNK1MKNK2CACNA1BMAPT | |
| SCHEMBL9434190 | 0.83 | CACNA1B (0.59) | CACNA1BALDH1A1 | |
| SCHEMBL9433588 | 0.83 | MAPT (0.42) | GAACACNA1BKDM4EMAPTALDH1A1 | |
| SCHEMBL9434815 | 0.82 | CACNA1C (0.44) | GAACACNA1BKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |