Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433816 | 0.89 | CACNA1C (0.46) | CACNA1CCACNA1BMAPTKMT2ALMNA | |
| SCHEMBL9433824 | 0.86 | CACNA1B (0.43) | CACNA1CCACNA1BMAPTKMT2AMEN1 | |
| SCHEMBL9433545 | 0.85 | CACNA1B (0.44) | CACNA1CCACNA1BMAPTLMNAKDM4E | |
| SCHEMBL9433577 | 0.84 | PKM (0.47) | CACNA1CCACNA1BKDM4EBRAF | |
| SCHEMBL9434792 | 0.84 | CACNA1B (0.43) | CACNA1CCACNA1BMAPTALDH1A1GAA | |
| SCHEMBL9434851 | 0.84 | KDM4E (0.44) | CACNA1CCACNA1BKDM4EALDH1A1NPC1 | |
| SCHEMBL9433588 | 0.82 | MAPT (0.42) | CACNA1CCACNA1BMAPTKMT2AMEN1 | |
| SCHEMBL9433754 | 0.82 | GAA (0.44) | CACNA1BMAPTKMT2AMEN1LMNA | |
| SCHEMBL10642720 | 0.81 | KDM4E (0.47) | CACNA1CCACNA1BMAPTKMT2ALMNA | |
| SCHEMBL9434813 | 0.81 | KDM4E (0.41) | CACNA1CCACNA1BMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |