Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 3/20 | 0.51 |
| ▸ | SELE | P16581 | 3/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433896 | 0.88 | KDM4E (0.51) | ICAM1SELEVCAM1SMN1; SMN2POLB | |
| SCHEMBL9433491 | 0.86 | KDM4E (0.51) | ICAM1SELEVCAM1SMN1; SMN2KDM4E | |
| SCHEMBL9433019 | 0.83 | ICAM1 (0.48) | ICAM1SELEPOLBKDM4EALDH1A1 | |
| SCHEMBL10373467 | 0.82 | KDM4E (0.51) | ICAM1SELEVCAM1SMN1; SMN2POLB | |
| SCHEMBL9432880 | 0.82 | KDM4E (0.47) | SMN1; SMN2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9433079 | 0.81 | EDNRA (0.51) | PARP10NPC1RAB9A | |
| SCHEMBL9433908 | 0.80 | IRAK4 (0.46) | ICAM1SELESMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9433742 | 0.79 | RXRA (0.43) | SMN1; SMN2POLBKDM4EALDH1A1HPGD | |
| SCHEMBL9433674 | 0.77 | ICAM1 (0.56) | ICAM1SELEVCAM1SMN1; SMN2POLB | |
| SCHEMBL9432935 | 0.77 | TP53 (0.50) | SMN1; SMN2POLBKDM4ETP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |