Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432939 | 0.90 | RXRA (0.48) | RXRARXRBMEN1MAPTKMT2A | |
| SCHEMBL27280518 | 0.86 | NR4A2 (0.44) | RXRARXRBMEN1MAPTKMT2A | |
| SCHEMBL9433908 | 0.83 | IRAK4 (0.46) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL9432880 | 0.80 | KDM4E (0.47) | SMN1; SMN2LMNAIRAK4GAAALDH1A1 | |
| SCHEMBL9433688 | 0.79 | ICAM1 (0.51) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL9433079 | 0.79 | EDNRA (0.51) | PKMNPC1CASP3RAB9ASENP8 | |
| SCHEMBL9433730 | 0.79 | KDM4E (0.43) | RXRARXRBMEN1MAPTKMT2A | |
| SCHEMBL10375126 | 0.76 | ADCY1 (0.37) | RXRARXRBMEN1MAPTKMT2A | |
| SCHEMBL10374754 | 0.74 | NR4A2 (0.41) | ALDH1A1BRD4HPGDKDM4E | |
| SCHEMBL9434171 | 0.73 | KMT2A (0.40) | RXRARXRBMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |