Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434171 | 0.85 | KMT2A (0.40) | IRAK4ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9433742 | 0.83 | RXRA (0.43) | IRAK4ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9433019 | 0.82 | ICAM1 (0.48) | IRAK4PARP10ALDH1A1GAAKDM4E | |
| SCHEMBL9433179 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL9432880 | 0.81 | KDM4E (0.47) | IRAK4PARP10ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9433688 | 0.80 | ICAM1 (0.51) | PARP10ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9433079 | 0.78 | EDNRA (0.51) | PARP10ACHE | |
| SCHEMBL9433895 | 0.75 | KDM4E (0.47) | IRAK4ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2790486 | 0.72 | KDM4E (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL9432939 | 0.71 | RXRA (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |