Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434014 | 0.88 | KDM4E (0.45) | CACNA1BKMOMKNK1MKNK2KDM4E | |
| SCHEMBL9434688 | 0.88 | KDM4E (0.47) | KDM4ELMNAHTTGAASMN1; SMN2 | |
| SCHEMBL9434851 | 0.87 | KDM4E (0.44) | CACNA1BMKNK1MKNK2KDM4EIRAK4 | |
| SCHEMBL9434417 | 0.84 | MAPT (0.45) | CACNA1BMKNK1MKNK2KDM4EHTT | |
| SCHEMBL9434642 | 0.83 | CACNA1B (0.52) | CACNA1B | |
| SCHEMBL9434087 | 0.83 | CACNA1B (0.43) | CACNA1BKMOMKNK1MKNK2KDM4E | |
| SCHEMBL9434755 | 0.81 | CACNA1B (0.45) | CACNA1BKMOMKNK1MKNK2KDM4E | |
| SCHEMBL9433669 | 0.81 | ALDH1A1 (0.47) | CACNA1BKMOKDM4ELMNAHTT | |
| SCHEMBL9433545 | 0.80 | CACNA1B (0.44) | CACNA1BKMOMKNK1MKNK2KDM4E | |
| SCHEMBL10432705 | 0.80 | CACNA1B (0.44) | CACNA1BKMOMKNK1MKNK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |