Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432765 | 0.83 | EDNRA (0.50) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL9434162 | 0.82 | CASP3 (0.58) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL9434241 | 0.80 | KDM4E (0.57) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL9432759 | 0.75 | EDNRA (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL629952 | 0.75 | MAOB (0.74) | MAOBLMNAHPGDNPC1RAB9A | |
| SCHEMBL10370975 | 0.74 | KDM4E (0.57) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL2761681 | 0.74 | MAOB (0.62) | CASP3SENP8SENP7SENP6MAOB | |
| SCHEMBL2762010 | 0.74 | L3MBTL1 (0.58) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29717105 | 0.74 | MAOB (0.63) | MAOBLMNAHPGDNPC1RAB9A | |
| SCHEMBL710202 | 0.74 | MAOB (0.63) | MAOBLMNAHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |