Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | CASP7 | P55210 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434755 | 0.91 | CACNA1B (0.45) | CACNA1BALDH1A1GAAKDM4EHPGD | |
| SCHEMBL10432705 | 0.89 | CACNA1B (0.44) | CACNA1BALDH1A1GAAKDM4EHPGD | |
| SCHEMBL9434417 | 0.88 | MAPT (0.45) | CACNA1BALDH1A1GAAKDM4EHPGD | |
| SCHEMBL9433919 | 0.88 | CACNA1B (0.44) | CACNA1BALDH1A1GAAKDM4EHPGD | |
| SCHEMBL9434042 | 0.88 | CACNA1B (0.48) | CACNA1BALDH1A1GAAKDM4EHPGD | |
| SCHEMBL9433659 | 0.88 | TSHR (0.46) | ALDH1A1GAAKDM4EHPGDCASP1 | |
| SCHEMBL9434041 | 0.86 | CACNA1B (0.42) | CACNA1BALDH1A1GAAKDM4EHPGD | |
| SCHEMBL9433821 | 0.86 | ALDH1A1 (0.46) | CACNA1BALDH1A1GAAKDM4EHPGD | |
| SCHEMBL9433669 | 0.83 | ALDH1A1 (0.47) | CACNA1BALDH1A1GAAKDM4EHPGD | |
| SCHEMBL9433824 | 0.83 | CACNA1B (0.43) | CACNA1BALDH1A1GAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |