Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | CASP7 | P55210 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434755 | 0.91 | CACNA1B (0.45) | CACNA1BKMT2AALDH1A1KDM4EGAA | |
| SCHEMBL10432705 | 0.89 | CACNA1B (0.44) | CACNA1BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL9434417 | 0.88 | MAPT (0.45) | CACNA1BKMT2AALDH1A1KDM4EGAA | |
| SCHEMBL9434316 | 0.88 | CACNA1B (0.44) | CACNA1BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL9433827 | 0.88 | CACNA1B (0.48) | CACNA1BKMT2ARXFP1ALDH1A1KDM4E | |
| SCHEMBL10432690 | 0.88 | HSD17B10 (0.48) | KMT2AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL9434041 | 0.86 | CACNA1B (0.42) | CACNA1BKMT2AALDH1A1KDM4EGAA | |
| SCHEMBL9433821 | 0.86 | ALDH1A1 (0.46) | CACNA1BKMT2AALDH1A1KDM4EGAA | |
| SCHEMBL9433669 | 0.83 | ALDH1A1 (0.47) | CACNA1BKMT2AALDH1A1KDM4EGAA | |
| SCHEMBL9434792 | 0.83 | CACNA1B (0.43) | CACNA1BALDH1A1GAAMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |