Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 12/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 12/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 8/20 | 0.42 |
| ▸ | KCNJ8 | Q15842 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347337 | 0.85 | KMT2A (0.47) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL8775041 | 0.85 | KMT2A (0.47) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL7347329 | 0.85 | KMT2A (0.47) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL7347332 | 0.85 | KMT2A (0.47) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL11165563 | 0.83 | LMNA (0.50) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL11160950 | 0.79 | ABCC9 (0.51) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL9456838 | 0.79 | ABCC9 (0.51) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| Hydrochloric Acid SCHEMBL10447525 | 0.78 | ABCC9 (0.50) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL11163664 | 0.78 | ABCC9 (0.47) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL11156357 | 0.77 | RAB9A (0.57) | ABCC9KCNJ11ABCC8KCNJ8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994004499-A1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS | THE UPJOHN COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |