Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9663251 | 0.86 | HSP90AA1 (0.41) | KDM4EPOLBMEN1KMT2ARAB9A | |
| SCHEMBL8544322 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1HTTPOLBMEN1 | |
| SCHEMBL9434971 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1HTTPOLBMEN1 | |
| SCHEMBL9318636 | 0.79 | SLC6A3 (0.47) | KDM4EALDH1A1HTTPOLBMEN1 | |
| SCHEMBL8548840 | 0.76 | KDM4E (0.35) | KDM4EALDH1A1HTTPOLBMEN1 | |
| SCHEMBL9318361 | 0.73 | AR (0.38) | KDM4EALDH1A1HTTPOLBMEN1 | |
| SCHEMBL5106474 | 0.70 | S1PR4 (0.50) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL4253395 | 0.68 | GRM2 (0.48) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL5100118 | 0.68 | MAPT (0.60) | KDM4EALDH1A1HTTPOLBMEN1 | |
| SCHEMBL3913935 | 0.67 | L3MBTL1 (0.59) | KDM4EALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994011369-A1 | ANTIHYPERTENSIVE 5-[(IMIDAZO[4,5-b]PYRIDIN-3-YL)METHYL]BENZOFURAN DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1994-05-26 | — | — | WO | disclosed |