Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.39 |
| ▸ | IGF1R | P08069 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2299321 | 0.77 | DRD4 (0.50) | SLC6A2SLC6A3HTR2AHTR2BHTR2C | |
| SCHEMBL3118428 | 0.75 | NAAA (0.48) | CA1CA2DRD4 | |
| SCHEMBL3113350 | 0.75 | CARM1 (0.51) | SLC6A2SLC6A3HTR2AHTR2BHTR2C | |
| SCHEMBL3121141 | 0.75 | CARM1 (0.51) | SLC6A2SLC6A3HTR2AHTR2BHTR2C | |
| SCHEMBL2300380 | 0.74 | OPRM1 (0.51) | SLC6A2SLC6A3HTR2AHTR2BHTR2C | |
| SCHEMBL3114317 | 0.73 | CARM1 (0.55) | HTR2BHTR2CSLC6A4CYP3A4 | |
| SCHEMBL3126964 | 0.73 | CARM1 (0.55) | SLC6A2SLC6A3SLC6A4DRD4 | |
| SCHEMBL3118807 | 0.73 | IDO1 (0.49) | SLC6A2SLC6A3HTR2AHTR2BHTR2C | |
| SCHEMBL3128435 | 0.72 | SLC6A4 (0.45) | SLC6A2SLC6A3HTR2AHTR2BHTR2C | |
| SCHEMBL3122265 | 0.72 | KIF11 (0.39) | SLC6A2SLC6A3HTR2AHTR2BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994000432-A1 | ANORECTIC EPINEPHRINE DERIVATIVES | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-01-06 | — | — | WO | disclosed |