Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435367 | 0.88 | ALDH1A1 (0.40) | MDM2ALDH1A1KDM4EOPRL1KMT2A | |
| SCHEMBL9434743 | 0.86 | KDM4E (0.43) | ALDH1A1KDM4EOPRL1KMT2ASMN1; SMN2 | |
| SCHEMBL9434908 | 0.86 | KAT2B (0.39) | L3MBTL1OPRL1SMN1; SMN2 | |
| SCHEMBL9435400 | 0.83 | MDM2 (0.40) | MDM2ALDH1A1 | |
| SCHEMBL9435298 | 0.75 | MEN1 (0.40) | ALDH1A1KDM4EKMT2AGAASMN1; SMN2 | |
| SCHEMBL9435270 | 0.74 | KAT2B (0.41) | L3MBTL1 | |
| SCHEMBL191324 | 0.63 | CYP4F2 (0.63) | ALDH1A1L3MBTL1KMT2AGAAMEN1 | |
| SCHEMBL27033354 | 0.62 | LMNA (0.57) | ALDH1A1KDM4EKMT2AGAASMN1; SMN2 | |
| SCHEMBL15778834 | 0.61 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL5163732 | 0.61 | GSK3A (0.66) | ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1095711-A | New pyrroline derivative contains their pharmaceutical composition and preparation method thereof | RICHTER GEDEON VEGYESZET (HU) | 1994-11-30 | — | — | CN | disclosed |
| WO-1994014768-A1 | NOVEL PYRROLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1994-07-07 | — | — | WO | disclosed |