SCHEMBL5163732

SCHEMBL5163732

COC(=O)CN1C(=O)C=CC1=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 2/20 0.66
GSK3B P49841 2/20 0.66
ALDH1A1 P00352 4/20 0.52
BLM P54132 2/20 0.52
CYP1A2 P05177 1/20 0.52
HPGD P15428 1/20 0.52
CYP2C19 P33261 1/20 0.52
WRN Q14191 1/20 0.52
HIF1A Q16665 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.45
LMNA P02545 2/20 0.44
GMNN O75496 1/20 0.44
MAPT P10636 1/20 0.44
THPO P40225 1/20 0.44
PMP22 Q01453 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MGLL Q99685 1/20 0.44
KAT2B Q92831 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12749846 0.80 GSK3A (0.74) GSK3AGSK3BALDH1A1BLMCYP1A2
SCHEMBL6422039 0.80 GSK3A (0.45) GSK3AGSK3BALDH1A1BLMCYP1A2
SCHEMBL5165436 0.79 KAT2B (0.49) GSK3AGSK3BALDH1A1BLMCYP1A2
SCHEMBL3384734 0.79 GSK3A (1.00) GSK3AGSK3BALDH1A1BLMCYP1A2
SCHEMBL13323652 0.79 GSK3A (0.52) GSK3AGSK3BALDH1A1BLMCYP1A2
SCHEMBL7097517 0.79 GSK3A (0.66) GSK3AGSK3BALDH1A1BLMCYP1A2
SCHEMBL14789789 0.78 GSK3A (0.59) GSK3AGSK3BALDH1A1BLMCYP1A2
SCHEMBL14423073 0.77 GSK3A (0.58) GSK3AGSK3BALDH1A1BLMCYP1A2
SCHEMBL5165562 0.76 GSK3A (0.73) GSK3AGSK3BALDH1A1BLMCYP1A2
SCHEMBL5161619 0.76 MGLL (0.54) GSK3AGSK3BALDH1A1BLMCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795195-B2 Antibody-drug conjugates including hemiasterlin derivative Sumitomo Pharma Co., Ltd. (JP) 2023-10-24 US disclosed
US-11760934-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display element in which the compound is used DIC CORPORATION (JP) 2023-09-19 US disclosed
US-11760934-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display element in which the compound is used DIC CORPORATION (JP) 2023-09-19 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11639327-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2023-05-02 US disclosed
US-11174217-B2 Polymerizable compound and liquid crystal composition DIC CORPORATION (JP) 2021-11-16 US disclosed
US-20210284766-A1 RETARDATION FILM, ELLIPTICALLY POLARIZING PLATE, AND DISPLAY DEVICE INCLUDING THE SAME DIC CORPORATION (JP) 2021-09-16 US disclosed
US-10947403-B2 Dispersion and inkjet ink composition, light conversion layer, and liquid crystal display element using the dispersion DIC CORPORATION (JP) 2021-03-16 US disclosed
US-10914987-B2 Complex and optical element KYOTO UNIVERSITY (JP) 2021-02-09 US disclosed
EP-1509555-B1 POLYVINYL ETHERS IMP COLLEGE INNOVATIONS LTD (GB) 2007-10-17 EP disclosed
EP-1582548-B1 PROCESS FOR PRODUCING POLYMERIZABLE POLYBRANCHED POLYESTER DAINIPPON INK & CHEMICALS (JP) 2007-03-28 EP disclosed
CN-1303130-C Process for producing polymerizable polybranched polyester DAINIPPON INK & CHEMICALS (JP) 2007-03-07 CN disclosed
US-7169829-B2 Maleimido-bearing compounds resin composition containing the same and cured articles thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-01-30 US disclosed
US-7141642-B2 Process for producing polymerizable polybranched polyester DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-11-28 US disclosed
US-20060047140-A1 Process for producing polymerizable polybranched polyester DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-03-02 US disclosed
CN-1714113-A Process for producing polymerizable polybranched polyester DAINIPPON INK & CHEMICALS (JP) 2005-12-28 CN disclosed
EP-1582548-A1 PROCESS FOR PRODUCING POLYMERIZABLE POLYBRANCHED POLYESTER DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-05 EP disclosed
CN-1454400-A Polymer solid electrolyte and battery using the same DAINIPPON INK & CHEMICALS (JP) 2003-11-05 CN disclosed
EP-1339127-A1 SOLID POLYMER ELECTROLYTE AND CELL CONTAINING THE ELECTROLYTE DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 GSK3A 1255/4885GSK3B 949/4885ALDH1A1 3448/4885
US-11760934-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display element in which the compound is used SFXN1, SFXN3, SIK3 GSK3A 2145/4885GSK3B 2101/4885ALDH1A1 3883/4885
US-11174217-B2 Polymerizable compound and liquid crystal composition PI4KA, PKN2, KCNH3 GSK3A 640/4885GSK3B 707/4885ALDH1A1 2918/4885
US-11795195-B2 Antibody-drug conjugates including hemiasterlin derivative HSD3B2, HSD3B1, HSD11B2 GSK3A 333/4885GSK3B 229/4885ALDH1A1 1287/4885
US-20060047140-A1 Process for producing polymerizable polybranched polyester ACSL4, ACSL1, HACL2 GSK3A 2879/4885GSK3B 3375/4885ALDH1A1 1751/4885
US-11639327-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display device using the same SKP1, PKN1, KTN1 GSK3A 718/4885GSK3B 485/4885ALDH1A1 3442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.