Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407602 | 0.88 | ALDH1A1 (0.40) | GAAKAT2BALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9435367 | 0.87 | ALDH1A1 (0.40) | MEN1GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL9435270 | 0.83 | KAT2B (0.41) | KAT2B | |
| SCHEMBL9435349 | 0.75 | MDM2 (0.42) | MEN1GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL2569441 | 0.64 | L3MBTL1 (0.55) | KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5165436 | 0.64 | KAT2B (0.49) | KAT2BALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL1928824 | 0.62 | PLAAT3 (0.51) | ALDH1A1 | |
| SCHEMBL16297223 | 0.60 | GAA (0.49) | MEN1GAAKMT2AP2RX3HSD17B10 | |
| SCHEMBL12370800 | 0.60 | HRH3 (0.53) | KMT2AALDH1A1KDM4E | |
| SCHEMBL18657080 | 0.60 | CYP4Z1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994014768-A1 | NOVEL PYRROLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1994-07-07 | — | — | WO | disclosed |