SCHEMBL943564

SCHEMBL943564

O=C(O)CCOCC(COCCC(=O)O)(COCCC(=O)O)NC(=O)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA2 P00918 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL945241 0.79 CA14 (0.35)
SCHEMBL21131771 0.78 KDM4E (0.30)
SCHEMBL14474311 0.76 PHF8 (0.31)
SCHEMBL18965258 0.76 MEN1 (0.34) ALDH1A1MEN1KMT2A
SCHEMBL4638213 0.74 ALDH1A1 (0.40) ALDH1A1
SCHEMBL21286081 0.72 ALDH1A1 (0.39) ALDH1A1
SCHEMBL7048627 0.72 MEN1 (0.35) CA2MEN1KMT2A
SCHEMBL19379975 0.72 PHF8 (0.32)
SCHEMBL14343085 0.72 ALDH1A1 (0.35) ALDH1A1
SCHEMBL31121301 0.71 SMN1; SMN2 (0.48) ALDH1A1POLBSMN1; SMN2CA2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140023592-A1 SELF COUPLING RECOMBINANT ANTIBODY FUSION PROTEINS RWTH AACHEN (DE) 2014-01-23 US disclosed
EP-2587263-A1 Self coupling recombinant antibody fusion proteins Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2013-05-01 EP disclosed
US-20110014216-A1 Drug Transfer Based on Coenzyme A and Acyl Carrier Protein COVALYS BIOSCIENCES AG (CH) 2011-01-20 US disclosed
US-20110014216-A1 Drug Transfer Based on Coenzyme A and Acyl Carrier Protein COVALYS BIOSCIENCES AG (CH) 2011-01-20 US disclosed
US-20110014196-A1 Drug Transfer into Living Cells COVALYS BIOSCIENCES AG (CH) 2011-01-20 US disclosed
US-20110014196-A1 Drug Transfer into Living Cells COVALYS BIOSCIENCES AG (CH) 2011-01-20 US disclosed
US-20110014196-A1 Drug Transfer into Living Cells COVALYS BIOSCIENCES AG (CH) 2011-01-20 US disclosed
US-20110014216-A1 Drug Transfer Based on Coenzyme A and Acyl Carrier Protein COVALYS BIOSCIENCES AG (CH) 2011-01-20 US disclosed
US-20100183516-A1 SELF COUPLING RECOMBINANT ANTIBODY FUSION PROTEINS FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2010-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110014196-A1 Drug Transfer into Living Cells TSPO, MPI, ABCB1 ALDH1A1 1179/4885POLB 3741/4885SMN1; SMN2 2482/4885
US-20110014216-A1 Drug Transfer Based on Coenzyme A and Acyl Carrier Protein COASY, ACAT2, ACAT1 ALDH1A1 736/4885POLB 4629/4885SMN1; SMN2 4649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.