Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.71 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.65 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | FPR2 | P25090 | 4/20 | 0.58 |
| ▸ | CASR | P41180 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282040 | 0.92 | RAB9A (0.66) | RAB9ASMN1; SMN2NPC1MTNR1BSAE1 | |
| SCHEMBL23560422 | 0.87 | MTNR1B (0.57) | RAB9ANPC1MTNR1BMEN1KMT2A | |
| SCHEMBL8577837 | 0.86 | SMN1; SMN2 (0.68) | RAB9ASMN1; SMN2NPC1MTNR1BSAE1 | |
| SCHEMBL5786396 | 0.85 | MTNR1B (0.67) | RAB9ASMN1; SMN2NPC1MTNR1BMEN1 | |
| SCHEMBL11092496 | 0.85 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1SAE1UBA2 | |
| SCHEMBL4588526 | 0.84 | RAB9A (0.70) | RAB9ASMN1; SMN2NPC1SAE1UBA2 | |
| SCHEMBL10598972 | 0.83 | SMN1; SMN2 (0.64) | RAB9ASMN1; SMN2NPC1SAE1UBA2 | |
| SCHEMBL20708118 | 0.83 | SMN1; SMN2 (0.68) | RAB9ASMN1; SMN2NPC1SAE1UBA2 | |
| SCHEMBL17782894 | 0.83 | RAB9A (0.68) | RAB9ASMN1; SMN2NPC1SAE1UBA2 | |
| SCHEMBL24590128 | 0.83 | RAB9A (0.68) | RAB9ASMN1; SMN2NPC1MTNR1BSAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170290809-A1 | ANTIVIRAL AGENTS AND USES THEREOF | GRIFFITH UNIVERSITY (AU) | 2017-10-12 | — | — | US | disclosed |
| US-7662910-B2 | Inhibitors for the soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-16 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-5283362-A | Reacting with an amine, terminating the reaction before the formation of by-product | CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) | 1994-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290809-A1 | ANTIVIRAL AGENTS AND USES THEREOF | RNASE1, ENTPD5, ACE | RAB9A 1505/4885SMN1; SMN2 3429/4885NPC1 1326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.