Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17511876 | 0.80 | ALDH1A1 (0.34) | EGFRCYP2A6 | |
| SCHEMBL275946 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL276594 | 0.74 | PRKCZ (0.33) | — | |
| SCHEMBL7470846 | 0.73 | ALDH1A1 (0.46) | CYP2A6 | |
| SCHEMBL449815 | 0.71 | — | — | |
| SCHEMBL1451648 | 0.70 | HSD17B1 (0.38) | — | |
| SCHEMBL17511934 | 0.70 | ALDH1A1 (0.42) | EGFRCYP2A6 | |
| SCHEMBL2357716 | 0.70 | CYP1A2 (0.41) | CYP2A6 | |
| SCHEMBL2355470 | 0.70 | CYP1A2 (0.41) | CYP2A6 | |
| SCHEMBL451583 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 12829 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208970-A1 | SUBSTITUTED HYDANTOIN COMPOUNDS, METHODS FOR PREPARATION THEREOF AND USE THEREOF IN THE TREATMENT AND/OR PREVENTION OF A CORONA VIRUS DISEASE | CARLSSON JENS (SE) | 2024-06-27 | — | — | US | claimed |
| EP-4361141-A1 | PROTEIN DEGRADATION AGENT | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2024-05-01 | — | — | EP | claimed |
| US-20240115564-A1 | HTR1F ANTAGONISTS FOR IMPROVEMENT OF BETA CELL SURVIVAL AND FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-04-11 | — | — | US | claimed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117813306-A | Heterocyclic compounds as KRAS inhibitors, their preparation and therapeutic use | 上海科州药物研发有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117751105-A | Substituted hydantoin compounds, process for their preparation and their use in the treatment and/or prophylaxis of coronavirus diseases | J·卡尔松 | 2024-03-22 | — | — | CN | claimed |
| WO-2024046370-A1 | HETEROCYCLIC COMPOUNDS AS KRAS INHIBITORS, AND PREPARATION AND THERAPEUTIC USE THEREOF | 上海科州药物研发有限公司 | 2024-03-07 | — | — | WO | claimed |
| EP-4329757-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2024-03-06 | — | — | EP | claimed |
| EP-4329883-A1 | SUBSTITUTED HYDANTOIN COMPOUNDS, METHODS FOR PREPARATION THEREOF AND USE THEREOF IN THE TREATMENT AND/OR PREVENTION OF A CORONA VIRUS DISEASE | Carlsson, Jens (SE) | 2024-03-06 | — | — | EP | claimed |
| EP-3749631-B1 | TRIARYLMETHANE COMPOUNDS | MITSUBISHI GAS CHEMICAL CO (JP) | 2024-03-06 | — | — | EP | claimed |
| US-4757071-A | 1,4-dihydropyridine derivatives, and pharmaceutical compositions containing same, useful for treating cardiovascular diseases | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-07-12 | — | — | US | claimed |
| EP-0239874-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-07 | — | — | EP | claimed |
| EP-0230242-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | claimed |
| EP-0184841-A2 | 1,4-Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions containing same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1986-06-18 | — | — | EP | claimed |
| US-4524146-A | NERVOUS SYSTEM DISORDERS | CIBA-GEIGY CORPORATION (US) | 1985-06-18 | — | — | US | claimed |
| EP-0014402-B1 | NOVEL 20-0-ACYLMAYTANSINOIDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Takeda Chemical Industries, Ltd. (JP) | 1983-07-20 | — | — | EP | claimed |
| US-4307016-A | FUNGICIDES, PROTOZOACIDES OR ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-12-22 | — | — | US | claimed |
| US-4294757-A | BLEACHING CELLULOSE FIBERS AND ADDITION OF ALKALI METAL POLYPHOSPHATES AND ALKALI METAL DIETHYLENETRIAMINE PENTA(METHYLENE PHOSPHONAT) | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1981-10-13 | — | — | US | claimed |
| US-4256746-A | ANTITUMOR AGENTS; MICROBIOCIDES; MITOSIS | TAKEDA CHEMICAL INDUSTRIES (JP) | 1981-03-17 | — | — | US | claimed |
| US-4091103-A | HYPOTENSIVE, CARDIOACTIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1978-05-23 | — | — | US | claimed |