Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437603 | 0.88 | MEN1 (0.46) | RENSMN1; SMN2 | |
| SCHEMBL9437560 | 0.88 | KMT2A (0.41) | RENMMP2MMP9ADAMTS4 | |
| SCHEMBL9437648 | 0.86 | MMP2 (0.36) | RENSMN1; SMN2MMP2MMP9ADAMTS4 | |
| SCHEMBL9437553 | 0.82 | F2 (0.36) | TSHRSMN1; SMN2MMP2MMP9ADAMTS4 | |
| SCHEMBL7332174 | 0.81 | MMP2 (0.51) | HSD17B10CHRM1MMP2MMP9ADAMTS4 | |
| SCHEMBL7332179 | 0.81 | MMP2 (0.51) | HSD17B10CHRM1MMP2MMP9ADAMTS4 | |
| SCHEMBL9437655 | 0.80 | HSD17B10 (0.40) | HSD17B10CHRM1CTSBAVPR1AAVPR1B | |
| SCHEMBL9437588 | 0.77 | CHRM1 (0.41) | HSD17B10CHRM1CTSBAVPR1AAVPR1B | |
| SCHEMBL9437621 | 0.77 | HSD17B10 (0.39) | HSD17B10CHRM1CTSBAVPR1AAVPR1B | |
| SCHEMBL7338091 | 0.76 | ITGB3 (0.48) | HSD17B10CHRM1CTSBAVPR1BCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |