Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 5/20 | 0.34 |
| ▸ | MMP9 | P14780 | 4/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437560 | 0.88 | KMT2A (0.41) | MEN1KMT2AALDH1A1MMP2MMP9 | |
| SCHEMBL9437599 | 0.82 | CTSS (0.36) | F2GFERMEN1KMT2AALOX5AP | |
| SCHEMBL9437602 | 0.82 | F2 (0.36) | F2GFERMEN1KMT2AALDH1A1 | |
| SCHEMBL9437603 | 0.82 | MEN1 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9437646 | 0.82 | HSD17B10 (0.40) | MMP2MMP9ADAMTS4SMN1; SMN2TSHR | |
| SCHEMBL9437538 | 0.80 | ALDH1A1 (0.37) | F2GFERMEN1KMT2AALDH1A1 | |
| SCHEMBL9437648 | 0.79 | MMP2 (0.36) | MEN1KMT2AALDH1A1MMP2MMP9 | |
| SCHEMBL9437614 | 0.78 | F2 (0.36) | F2GFERMEN1KMT2AALDH1A1 | |
| SCHEMBL7338835 | 0.73 | REN (0.46) | — | |
| SCHEMBL7338208 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |