Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437734 | 0.97 | SIGMAR1 (0.47) | SIGMAR1ADRA2AADRA2BADRA2CHRH1 | |
| Hydrochloric Acid SCHEMBL9437809 | 0.88 | SIGMAR1 (0.42) | SIGMAR1ADRA2AADRA2BADRA2CHRH1 | |
| Hydrochloric Acid SCHEMBL9437903 | 0.86 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL9437736 | 0.82 | SIGMAR1 (0.43) | SIGMAR1ADRA2AADRA2BADRA2CHRH1 | |
| SCHEMBL9437791 | 0.82 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL9437725 | 0.80 | TSHR (0.44) | — | |
| SCHEMBL9437967 | 0.78 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL9437801 | 0.77 | HTR1A (0.40) | — | |
| SCHEMBL8948178 | 0.77 | SIGMAR1 (0.57) | SIGMAR1ADRA2AADRA2BADRA2CHRH1 | |
| SCHEMBL9437886 | 0.77 | PARP1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |