Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 7/20 | 0.34 |
| ▸ | REN | P00797 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | CTSL | P07711 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295043 | 1.00 | GAA (0.37) | GAATSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9439343 | 0.79 | CTSK (0.36) | CTSSRENCTSKCTSL | |
| SCHEMBL7303004 | 0.79 | CTSK (0.36) | CTSSRENCTSKCTSL | |
| SCHEMBL7295178 | 0.78 | PIK3CD (0.39) | GAATSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9439766 | 0.78 | PIK3CD (0.39) | GAATSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7268415 | 0.74 | CTSK (0.37) | ALDH1A1CTSSRENCTSKCTSL | |
| SCHEMBL7278776 | 0.72 | CTSK (0.42) | CTSSCTSKCTSL | |
| SCHEMBL7269844 | 0.72 | CTSK (0.42) | CTSSCTSKCTSL | |
| SCHEMBL3565758 | 0.72 | REN (0.39) | TSHRCTSSRENCTSK | |
| SCHEMBL3565755 | 0.72 | REN (0.39) | TSHRCTSSRENCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278148-A | Hypotensive agents | HOFFMANN-LA ROCHE INC. (US) | 1994-01-11 | — | — | US | disclosed |