Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 8/20 | 0.49 |
| ▸ | ATIC | P31939 | 2/20 | 0.44 |
| ▸ | FOLR1 | P15328 | 4/20 | 0.43 |
| ▸ | DHFR | P00374 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439698 | 0.90 | GART (0.48) | GARTATICFOLR1DHFR | |
| SCHEMBL9439574 | 0.86 | GART (0.62) | GARTATICFOLR1DHFR | |
| SCHEMBL8566521 | 0.85 | DHFR (0.46) | GARTDHFR | |
| SCHEMBL9439570 | 0.85 | GART (0.58) | GARTATICFOLR1DHFR | |
| SCHEMBL9758306 | 0.85 | DHFR (0.55) | GARTATICDHFR | |
| SCHEMBL8997170 | 0.85 | DHFR (0.55) | GARTATICDHFR | |
| SCHEMBL9041616 | 0.84 | GART (0.54) | GARTATICFOLR1 | |
| SCHEMBL9439622 | 0.84 | GART (0.48) | GARTATICFOLR1DHFR | |
| SCHEMBL9042993 | 0.84 | GART (0.48) | GARTATICFOLR1DHFR | |
| SCHEMBL9227822 | 0.82 | DHFR (0.52) | GARTATICDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354754-A | Antitumor and -carcinogenic agents; treating human epidermoid carcinoma KB | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |