Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.53 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9440688 | 0.87 | SIRT2 (0.51) | FOLH1MMP2MMP9SIRT2SIRT1 | |
| SCHEMBL7226853 | 0.83 | MMP2 (0.50) | MMP2MMP9ITGB3CPB1CPB2 | |
| SCHEMBL7226850 | 0.83 | MMP2 (0.50) | MMP2MMP9ITGB3CPB1CPB2 | |
| Methane SCHEMBL28261132 | 0.82 | MMP2 (0.49) | MMP2MMP9ITGB3CPB1CPB2 | |
| SCHEMBL3982664 | 0.82 | NPC1 (0.46) | MMP2MMP9ITGB3CPB1CPB2 | |
| SCHEMBL6158695 | 0.82 | CA1 (0.59) | MMP2SIRT2SIRT1 | |
| SCHEMBL6158692 | 0.82 | CA1 (0.59) | MMP2SIRT2SIRT1 | |
| SCHEMBL8702185 | 0.80 | MME (0.52) | FOLH1 | |
| SCHEMBL9556097 | 0.80 | LTA4H (0.46) | MMP2 | |
| SCHEMBL28937048 | 0.80 | LTA4H (0.46) | MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526488-B1 | BENZYLPHOSPHONIC ACID TYROSINE KINASE INHIBITORS | PFIZER (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1991015495-A1 | BENZYLPHOSPHONIC ACID TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1991-10-17 | — | — | WO | disclosed |