Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL9440449 | 0.94 | MAPT (0.47) | L3MBTL1LMNACA12CA1CA2 | |
| SCHEMBL11474832 | 0.90 | MAPT (0.47) | L3MBTL1LMNACA12CA1CA2 | |
| SCHEMBL3630216 | 0.83 | P4HTM (0.59) | L3MBTL1PLK1LMNAP4HTMMAPT | |
| SCHEMBL27812383 | 0.82 | L3MBTL1 (0.49) | L3MBTL1PLK1LMNAP4HTMLTA4H | |
| SCHEMBL6309786 | 0.82 | L3MBTL1 (0.45) | L3MBTL1PLK1LMNACA12CA1 | |
| SCHEMBL2274462 | 0.82 | P4HTM (0.58) | L3MBTL1PLK1LMNAP4HTMMAPT | |
| SCHEMBL24756726 | 0.77 | MAPT (0.49) | L3MBTL1LMNAMAPTKDM4EHPGD | |
| SCHEMBL1749748 | 0.77 | KDM4E (0.61) | L3MBTL1LMNAP4HTMMAPTKDM4E | |
| Zinc Ion SCHEMBL9440255 | 0.77 | ALDH1A1 (0.44) | L3MBTL1LMNACA2P4HTMMAPT | |
| SCHEMBL16011698 | 0.76 | P4HTM (0.58) | L3MBTL1LMNACA1CA2P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433457-B1 | ANTIPRURITIC COMPOSITION | SHISEIDO CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5219847-A | Antipruritic composition | SHISEIDO COMPANY, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0433457-A1 | ANTIPRURITIC COMPOSITION | SHISEIDO COMPANY LIMITED (JP) | 1991-06-26 | — | — | EP | disclosed |