Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474832 | 0.97 | MAPT (0.47) | MAPTKDM4EHPGDHTTHSD17B10 | |
| Zinc Ion SCHEMBL9440249 | 0.94 | L3MBTL1 (0.44) | MAPTKDM4EHPGDHTTHSD17B10 | |
| SCHEMBL24756726 | 0.83 | MAPT (0.49) | MAPTKDM4EHPGDHTTHSD17B10 | |
| SCHEMBL1749748 | 0.83 | KDM4E (0.61) | MAPTKDM4EHPGDHTTHSD17B10 | |
| Zinc Ion SCHEMBL9440255 | 0.82 | ALDH1A1 (0.44) | MAPTKDM4EHSD17B10KMT2ATSHR | |
| SCHEMBL11474833 | 0.82 | KDM4E (0.59) | MAPTKDM4EHPGDHTTHSD17B10 | |
| SCHEMBL2274826 | 0.82 | KDM4E (0.59) | MAPTKDM4EHPGDHTTHSD17B10 | |
| SCHEMBL26480953 | 0.82 | MAPT (0.48) | MAPTKDM4EHPGDHTTHSD17B10 | |
| SCHEMBL10664855 | 0.81 | TSHR (0.59) | MAPTKDM4EKMT2ATSHRTP53 | |
| SCHEMBL24757913 | 0.81 | TP53 (0.51) | MAPTKDM4EHPGDHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433457-B1 | ANTIPRURITIC COMPOSITION | SHISEIDO CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5219847-A | Antipruritic composition | SHISEIDO COMPANY, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0433457-A1 | ANTIPRURITIC COMPOSITION | SHISEIDO COMPANY LIMITED (JP) | 1991-06-26 | — | — | EP | disclosed |