Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440300 | 0.94 | KCNH2 (0.44) | ALDH1A1MAPK8TSHRKMT2AKCNH2 | |
| SCHEMBL7839773 | 0.80 | ALDH1A1 (0.58) | ALDH1A1 | |
| SCHEMBL2454329 | 0.79 | KCNH2 (0.42) | ALDH1A1MAPK8TSHRL3MBTL1KMT2A | |
| SCHEMBL11942197 | 0.78 | KCNH2 (0.44) | ALDH1A1TSHRL3MBTL1KMT2AKCNH2 | |
| SCHEMBL2460027 | 0.76 | KDM4E (0.50) | ALDH1A1MAPK8TSHRL3MBTL1TDP1 | |
| SCHEMBL2520179 | 0.76 | LTA4H (0.50) | ALDH1A1TSHRL3MBTL1KMT2AKCNH2 | |
| SCHEMBL11275809 | 0.75 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1KCNH2CYP1A2CYP2C19 | |
| SCHEMBL2270674 | 0.75 | KDM4E (0.48) | ALDH1A1MAPK8TSHRL3MBTL1TDP1 | |
| SCHEMBL13082211 | 0.75 | KCNH2 (0.39) | ALDH1A1MAPK8TSHRL3MBTL1TDP1 | |
| SCHEMBL3133224 | 0.75 | OPRM1 (0.43) | ALDH1A1MAPK8TSHRL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433457-B1 | ANTIPRURITIC COMPOSITION | SHISEIDO CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5219847-A | Antipruritic composition | SHISEIDO COMPANY, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0433457-A1 | ANTIPRURITIC COMPOSITION | SHISEIDO COMPANY LIMITED (JP) | 1991-06-26 | — | — | EP | disclosed |