Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGFBP3 | P17936 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.40 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.40 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904601 | 0.85 | IGFBP3 (0.50) | IGFBP3SLC6A2P2RY14KDM4EALDH1A1 | |
| SCHEMBL9441975 | 0.81 | ALOX15 (0.39) | IGFBP3ALDH1A1DHODHKMO | |
| SCHEMBL8337206 | 0.78 | DHODH (0.43) | IGFBP3ALDH1A1HPGDHSD17B10CYP2C9 | |
| SCHEMBL9441961 | 0.78 | MCL1 (0.43) | IGFBP3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL31329134 | 0.78 | MGAM (0.53) | IGFBP3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4307200 | 0.78 | MGAM (0.53) | IGFBP3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16759794 | 0.77 | ALOX15 (0.46) | IGFBP3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14578175 | 0.77 | ALOX15 (0.58) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL30120650 | 0.77 | KDM4E (0.49) | IGFBP3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28496945 | 0.77 | KDM4E (0.49) | IGFBP3KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250541-A | Neurological disorders | FIDIA S.P.A. (IT) | 1993-10-05 | — | — | US | disclosed |