Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.65 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.50 |
| ▸ | SELE | P16581 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL742273 | 0.87 | CTNNB1 (0.65) | CTNNB1KDM4CICAM1SELEALDH1A1 | |
| SCHEMBL238351 | 0.87 | KDM4C (0.59) | CTNNB1KDM4CALDH1A1MAPK1HSD17B10 | |
| SCHEMBL29131592 | 0.83 | ALDH1A1 (0.49) | CTNNB1ALDH1A1PTGS1PTGS2TDP1 | |
| SCHEMBL30602953 | 0.83 | ALDH1A1 (0.49) | CTNNB1ALDH1A1PTGS1PTGS2TDP1 | |
| SCHEMBL23012320 | 0.81 | TDP1 (0.55) | KDM4CALDH1A1MAPK1HSD17B10PTGS1 | |
| SCHEMBL17397069 | 0.80 | CTNNB1 (0.74) | CTNNB1KDM4CALDH1A1MAPK1HSD17B10 | |
| SCHEMBL30298696 | 0.80 | ICAM1 (0.59) | ICAM1SELEALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30341576 | 0.80 | ICAM1 (0.59) | ICAM1SELEALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1702138 | 0.79 | CTNNB1 (0.68) | CTNNB1ALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL30060692 | 0.79 | CTNNB1 (0.68) | CTNNB1ALDH1A1MAPK1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009437-A1 | CARBOXAMIDE-HETEROARYL DERIVATIVES FOR THE TREATMENT OF DIABETES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-01-13 | — | — | US | claimed |
| US-9695162-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20170029416-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2017-02-02 | — | — | US | disclosed |
| US-20110009437-A1 | CARBOXAMIDE-HETEROARYL DERIVATIVES FOR THE TREATMENT OF DIABETES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-01-13 | — | — | US | disclosed |
| EP-0447004-A2 | Herbicidal carboxamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009437-A1 | CARBOXAMIDE-HETEROARYL DERIVATIVES FOR THE TREATMENT OF DIABETES | GLS, GCKR, HK1 | CTNNB1 3140/4885KDM4C 1815/4885ICAM1 3675/4885 |
| US-20170029416-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | CTNNB1 4789/4885KDM4C 1407/4885ICAM1 3579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.