Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | MAOA | P21397 | 3/20 | 0.78 |
| ▸ | MAOB | P27338 | 2/20 | 0.78 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | ELANE | P08246 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aloe-Emodin SCHEMBL29814516 | 0.88 | MEN1 (1.00) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL29398579 | 0.88 | MEN1 (1.00) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL309756 | 0.88 | MEN1 (1.00) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL27902038 | 0.87 | MEN1 (0.71) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL28079854 | 0.85 | MEN1 (0.94) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL8827767 | 0.85 | MEN1 (0.94) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL16656216 | 0.84 | MAOA (0.58) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL23486119 | 0.83 | MEN1 (0.75) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL8996488 | 0.83 | MEN1 (0.75) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL11423804 | 0.83 | MEN1 (0.80) | MEN1KMT2AMAOAMAOBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525073-A1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. | DU PONT (US) | 1993-02-03 | — | — | EP | disclosed |