Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445923 | 1.00 | MEN1 (0.46) | MEN1KMT2AALDH1A1MEP1BHDAC1 | |
| SCHEMBL9445914 | 0.88 | MEN1 (0.48) | MEN1KMT2AALDH1A1MEP1BHDAC1 | |
| SCHEMBL9445912 | 0.88 | MEN1 (0.48) | MEN1KMT2AALDH1A1MEP1BHDAC1 | |
| SCHEMBL3390402 | 0.76 | CCNT1 (0.46) | HDAC1CCNT1CDK9 | |
| SCHEMBL9445917 | 0.76 | HDAC1 (0.41) | MEN1KMT2AALDH1A1MEP1BHDAC1 | |
| SCHEMBL24326690 | 0.75 | TRPM8 (0.59) | MEN1KMT2AALDH1A1MEP1BTRPM8 | |
| SCHEMBL1889631 | 0.75 | TRPM8 (0.59) | MEN1KMT2AALDH1A1MEP1BTRPM8 | |
| SCHEMBL1889629 | 0.75 | TRPM8 (0.59) | MEN1KMT2AALDH1A1MEP1BTRPM8 | |
| SCHEMBL1616321 | 0.74 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1MEP1BCYP2D6 | |
| Hydrochloric Acid SCHEMBL5808835 | 0.73 | TRPM8 (0.56) | MEN1KMT2AALDH1A1MEP1BTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |