Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445912 | 1.00 | MEN1 (0.48) | MEN1KMT2AMEP1BMAPTL3MBTL1 | |
| SCHEMBL9445926 | 0.88 | MEN1 (0.46) | MEN1KMT2AMEP1BHDAC1CCNT1 | |
| SCHEMBL9445923 | 0.88 | MEN1 (0.46) | MEN1KMT2AMEP1BHDAC1CCNT1 | |
| SCHEMBL9446006 | 0.80 | MAPT (0.39) | MAPTL3MBTL1ALDH1A1SCN9A | |
| SCHEMBL9446002 | 0.80 | MAPT (0.39) | MAPTL3MBTL1ALDH1A1SCN9A | |
| SCHEMBL3390402 | 0.78 | CCNT1 (0.46) | MAPTHDAC1CCNT1CDK9 | |
| SCHEMBL9445917 | 0.78 | HDAC1 (0.41) | MEN1KMT2AMEP1BHDAC1CCNT1 | |
| SCHEMBL1616460 | 0.76 | ALDH1A1 (0.58) | MEN1KMT2AMEP1BMAPTL3MBTL1 | |
| SCHEMBL1616311 | 0.76 | ALDH1A1 (0.58) | MEN1KMT2AMEP1BMAPTL3MBTL1 | |
| SCHEMBL498351 | 0.74 | LOXL2 (0.57) | MAPTHDAC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |