SCHEMBL9446142

SCHEMBL9446142

Oc1ccc(O)c(-c2ccccc2Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.49
CA9 Q16790 2/20 0.49
MIF P14174 1/20 0.49
ESR2 Q92731 3/20 0.47
ESR1 P03372 2/20 0.47
MAPT P10636 3/20 0.45
MEN1 O00255 2/20 0.45
HPGD P15428 2/20 0.45
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
HSD17B10 Q99714 2/20 0.45
ALOX15 P16050 1/20 0.45
ALOX12 P18054 1/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43
MAPK14 Q16539 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL48496 0.98 CA12 (0.47) CA12CA9MIFESR2ESR1
SCHEMBL28234020 0.85 ALOX5 (0.54) CA12CA9MIFESR2ESR1
SCHEMBL6269206 0.84 MAPT (0.61) MAPTMEN1HPGDKMT2ASMN1; SMN2
Methane SCHEMBL28112789 0.83 ALOX5 (0.52) CA12CA9MIFESR2ESR1
SCHEMBL4636219 0.82 ESR2 (0.55) CA12ESR2ESR1MAPTMEN1
SCHEMBL24042748 0.82 ESR2 (0.47) CA12CA9MIFESR2ESR1
SCHEMBL31621429 0.81 KMO (0.40) MIFESR2ESR1MAPTHSD17B10
SCHEMBL6573399 0.80 PLA2G7 (0.62) CA12CA9MAPTMEN1HPGD
SCHEMBL29807938 0.80 ALDH1A1 (0.62) CA12MAPTMEN1HPGDKMT2A
SCHEMBL1022489 0.80 ALDH1A1 (0.62) CA12MAPTMEN1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5235025-A Cross-linkable thermotropic liquid crystalline aromatic polyester HIMONT ITALIA S.R.L. (IT) 1993-08-10 US claimed
US-5082885-A Phenolic compound SHELL OIL COMPANY (US) 1992-01-21 US claimed
CN-102166404-B Multilayer core golf ball 阿库施耐特公司 2016-09-14 CN disclosed
CN-102166402-B Multilayer core golf ball 阿库施耐特公司 2016-08-03 CN disclosed
CN-1239453-C Polyether ketone kind rigid largering monomer, polymer and synthesis method UNIV JILIN (CN) 2006-02-01 CN disclosed
CN-1556085-A Polyether ketone kind rigid largering monomer, polymer and synthesis method 吉林大学 2004-12-22 CN disclosed
US-5235025-A Cross-linkable thermotropic liquid crystalline aromatic polyester HIMONT ITALIA S.R.L. (IT) 1993-08-10 US disclosed
US-5082885-A Phenolic compound SHELL OIL COMPANY (US) 1992-01-21 US disclosed
EP-0383177-A2 Cross-linkable thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-08-22 EP disclosed
EP-0262900-A2 Anisotropic melt polyesters with improved glass transition temperature E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-04-06 EP disclosed
EP-0032063-B1 NOVEL SUBSTITUTED ARYLENE COMPOUNDS AND PROCESSES FOR THEIR PRODUCTION WARNER-LAMBERT COMPANY (US) 1984-03-14 EP disclosed
US-4351950-A Anti-arteriosclerotic agents WARNER-LAMBERT COMPANY (US) 1982-09-28 US disclosed
EP-0032063-A2 Novel substituted arylene compounds and processes for their production WARNER-LAMBERT COMPANY (US) 1981-07-15 EP disclosed
EP-0011295-A1 Yellow monoazo dyes of the 2-hydroxydibenzofuran series; their preparation and use for dyeing and printing synthetic hydrophobic fibres Montedison S.p.A. (IT) 1980-05-28 EP disclosed